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In the U.S., ultraviolet (UV) reactors are currently validated using coliphage MS2 as the challenge microbe;however, MS2 is significantly more UV-resistant than Cryptosporidium parvum. The objectiveof this study was to characterize the UV dose response of microorganisms that better match thedose response of Cryptosporidium than does MS2. The overall approach was to select andacquire potential surrogate microorganisms identified from a thorough literature search andperform bench-scale testing of the prospective surrogates to determine their dose responses toUV irradiation. Of these candidate organisms, only those that demonstrated dose responsessimilar to C. parvum were further characterized. Methodologies to maximize microorganismyield for large scale propagation (a required characteristic of the virus surrogate) were developedand used to further screen the potential usefulness of the selected organisms. Based on thesefindings, the surrogate(s) that most closely resembled Cryptosporidium's response to UV wasselected for full-scale testing. Includes figure.

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Edition: Vol. - No. Published: 11/15/2004 Number of Pages: 5File Size: 1 file , 290 KB